DEFAME is a playable word

defame Scrabble® Dictionary

verb
defamed, defaming, defames
to attack the good name of
38 Playable Words can be made from "DEFAME"
   2-Letter Words (12 found)
   3-Letter Words (11 found)
   4-Letter Words (11 found)
   5-Letter Words (3 found)
   6-Letter Words (1 found)