LOCOS is a playable word

loco Scrabble® Dictionary

noun
pl. locos or locoes
locoweed
verb
locoed, locoing, locos
to poison with locoweed
17 Playable Words can be made from "LOCOS"
   2-Letter Words (3 found)
   3-Letter Words (6 found)
   4-Letter Words (6 found)
   5-Letter Words (2 found)