SEMEME is a playable word

sememe Scrabble® Dictionary

noun
pl. sememes
the meaning of a morpheme
(adjective) sememic
16 Playable Words can be made from "SEMEME"
   2-Letter Words (4 found)
   3-Letter Words (4 found)
   4-Letter Words (5 found)
   5-Letter Words (2 found)
   6-Letter Words (1 found)